|
Date
|
Treatment
|
Scans
|
Appointments / Notes
|
|
2003
|
|
|
|
|
Nov 2003
|
Saw family doctor for shoulder pain. X-ray revealed lesion in glenoid of
scapula. Sarcoma or Lymphoma suspected.
|
|
Dr. William Roes, family doctor |
| Dec 2003 |
Biopsy performed by Dr. Chappy Conrad, Univ. of WA. Diagnosed with Non
Small Cell Adenocarcinoma (Lung Cancer), Stage IV
2.5 cm mass in upper right lobe and numerous small nodules throughout
both lungs, bone met to right scapula, mediastinal lymph node
involvement in center of chest.
Never smoked, never around smokers, no cancer in
family.
|
|
Under care of Dr. Frank Senecal, Hematology Oncology Northwest, Tacoma, WA. |
|
Dec. 22, 2003
|
Chemo #1 Taxol/Carboplatin
|
|
every 21 days
|
|
2004
|
Treatment
|
Scans
|
Appointments / Notes
|
| Jan. 12, 2004 |
Chemo #2 Taxol/Carboplatin
|
|
Also seeing Dr. Mark Gignac, ND, Seattle Cancer Treatment & Wellness
Center.
|
|
|
|
Scans show slight improvement in lung
|
|
|
Feb. 3, 2004
|
Chemo #3 Taxol/Carboplatin
|
|
|
|
Feb 24, 2004
|
Chemo #4 Taxol/Carboplatin
|
|
Very few side effects, blood counts good..
|
|
|
Also getting Zometa with chemo to strengthen bone.
|
|
|
|
Mar 4, 2004
|
|
Scans show no change
|
|
|
Mar 14, 2004
|
|
|
Started Vioxx (Cox 2 inhibitor) to perhaps enhance chemo.
|
|
Mar 15, 2004
|
Chemo #5 of Taxol/Carboplatin
|
|
|
|
Apr 5, 2004
|
Chemo #6 Taxol/Carboplatin
|
|
Apr 9, 2004
|
|
|
Decided to stop taking Vioxx based on additional info I've learned.
|
|
|
|
|
Dr. Senecal consulted with Dr. V. Miller at Sloan Kettering upon my
request to discuss possible use of Iressa in combination with chemo. Dr.
Miller has special interest in never-smokers and says data shows that
non smoking women have best response to Iressa.
|
| Apr 21, 2004 |
|
Chest CT - stable
Pelvic CT - stable
Brain MRI - negative
|
|
|
Apr 22, 2004
|
|
Shoulder MRI - no significant change
|
|
|
Apr 22, 2004
|
|
EGFR Cell Test Results: Uniform EGFR +3
|
|
|
Apr 27, 2004
|
Started Iressa
|
|
a daily targeted drug therapy. Epidermal Growth Factor Receptor
Inhibitor.
|
| May 3, 2004 |
Zometa
|
|
|
|
May 4, 2004
|
|
|
Developed wheeze with deep inhale
|
|
May 6, 2004
|
Stopped Iressa to see if wheeze decreases
|
|
|
|
May 14, 2004
|
Started Iressa again
|
Chest CT Angiogram Technique - Stable
|
(not sure of exact date)
|
|
May 21, 2004
|
|
|
Saw Dr. Rai, pulmonologist regarding wheeze. Scheduled Bronchoscopy.
|
|
May 24, 2004
|
Bronchoscopy. - Inflammation in right bronchi but biopsy was negative.
Unsure why there's inflammation.
Back on Iressa.
|
|
|
|
June 10, 2004
|
Pulmonary function test - normal gas exchange, normal volume, but some
obstruction.
|
|
|
|
June 15, 2004
|
|
Shoulder MRI - marked improvement
|
|
|
June 17, 2004
|
|
Brain MRI - negative
|
|
|
June 21, 2004
|
|
Chest CT - stable
|
|
|
June 24, 2004
|
|
|
Back on Vioxx.
|
| June 28, 2004 |
Zometa
|
|
|
|
July 7, 2004
|
|
|
Dr. Rai - pulmonologist. He still thinks wheeze may be asthma but is
keeping an eye on it. May have second bronchoscopy in future.
|
|
Aug. 17, 2004
|
|
Brain & Chest CT - Stable
|
|
|
Aug. 31, 2004
|
|
PET Scan - lesion in shoulder no longer visible. Mass in lung
shows max SUV of 1.2 (extremely low activity). (A PET scan shows
cell activity, not just physical abnormalities like CTs and MRIs do.)
|
|
|
Oct. 29, 2004
|
|
Chest, Abdomen, Pelivic CT - possibly 2 new nodules in lung, possible
growth of primary tumor in lung. Waiting for PET scan to confirm.
|
|
|
Nov. 11, 2004
|
|
Shoulder MRI - showed improvement (more healing of lesion) however PET
scan will determine for sure if current pain is caused from progression
or not.
|
|
|
Dec. 3 2004
|
|
PET scan - Extremely low activity. Max SUV 1.2
|
|
|
2005
|
Treatment
|
Scans
|
Appointments / Notes
|
| Feb. 18 2005 |
|
Brain MRI - 7 brain mets. Largest is 8 mm. No symptoms.
Chest CT - Lungs still appear stable.
|
|
|
Mar.1 2005
|
Whole Brain
Radiation with Temodor |
|
Daily for 4 1/2 wks. Completed treatment
April 1. Stopped Iressa during WBR |
|
April 15 2005
|
Started Tarceva
|
|
Did not fail Iressa but switched to
Tarceva because data showed it may work a little better. |
| May 6 2005 |
|
PET Scan - everything stable (below the head). Max SUV 1.1 at primary
tumor. No other activity detected.
|
|
|
May 12 2005
|
|
Brain MRI - Marked improvement
|
|
|
July 2005
|
|
Brain MRI - all but one met gone. Remaining one appears inactive. Chest,
Abodoman, Pelvis CT - stable
|
|
|
Sept.12 2005
|
|
Brain MRI - clean, no sign of metastatic disease
|
|
|
Sept 13 2005
|
|
PET Scan - lungs stable, new activity in shoulder lesion
|
|
|
Sept. 22 2005
|
|
MRI Shoulder - confirmed activity
|
|
|
Sept. 27 -Oct.18 2005
|
Radiation to shoulder
|
|
|
|
Nov 82005
|
|
Brain MRI - looks good
Chest CT - stable, no sign of growth
|
|
|
Nov 20 2005
|
|
Shoulder MRI - improvement
|
|
|
2006
|
Treatment
|
Scans
|
Appointments / Notes
|
| Jan 6 2006 |
|
Chest CT- no change
Brain MRI - no change
|
|
|
Jan 24 2006
|
|
PET Scan - stable. Active in shoulder but attributed to
radiation/healing.
|
|
|
Ap 11 2006
|
|
Shoulder MRI - tumor has grown according to local radiologist.
|
Shoulder Pain prompted MRI
|
|
Ap 20 2006
|
|
Brain MRI - no significant change
Chest/Pelvic CT - stable
|
|
|
Ap 25 2006
|
|
|
Saw Dr. Conrad at SCCA - wants to wait 2 months and scan again to
confirm shoulder lesion is progressing
|
|
May 9 2006
|
|
|
Due to increased pain, saw Dr. Conrad. Ordered MRI.
|
|
May 12 2006
|
|
Shoulder MRI - could not complete due to pain.
|
(Used 10 mg Valium and 1 Oxycontin)
|
|
May 17 2006
|
|
Shoulder MRI . - inconclusive.
Wait longer and rescan. Dr. Conrad viewed film.
|
at hospital with 10 mg morphine IV
|
|
June 6 2006
|
|
|
Saw Dr. Conrad - scans still inconclusive. Scheduled for surgery to take
a look and repair damage to shoulder.
|
|
July 7 2006
|
|
PET Scan (with 10 mg Valium & 2 Dolodid for pain) - Everything still
stable except for shoulder with SUV of 4.
|
|
|
July 11 2006
|
|
Brain MRI - ok
Chest CT - Nodule in lower right lobe of lung has increased in size from
3 mm to 6 mm. New spot in middle right lobe is inconclusive.
Shoulder CT -
|
|
| July 20 2006 |
|
|
Shoulder Surgery at U of W Medical Center. CANCELLED. Dr. Conrad feels
surgery is too risky and may cause more damage to the bone than is
already there.
|
|
Aug 3 2006
|
|
|
Dr. Senecal - we decided to wait and scan in 3 weeks to get better
picture of progression and determine treatment then.
|
|
Aug. 22 2006
|
|
Chest CT - 3 tumors have increased in size
Shoulder CT - stable
|
|
|
Aug 24 2006
|
|
Brain MRI - fine
|
Met with Dr. Sencal to go over results.
|
|
Aug 30 2006
|
|
|
B12 injection (in prep for Alimta)
Left elbow became infected. Went to Urgent Care. Started on Keflex.
|
|
Aug 31 2006
|
|
|
Saw family doctor. Changed to Clindimyacin and Ramamfin.
|
|
Sept. 1 2006
|
|
|
Saw Infectious Disease Doctor and started on 14 day IV antibiotics for
staph infection. Had 5 infusions then to orals on 9/6.
|
|
Sept 11 2006
|
#1 Alimta/Avastin - Chemo Infusion
|
|
minimal side effects
|
| Oct. 2 2006 |
#2 Alimta/Avastin - Chemo Infusion
|
|
some side effects, some nausea and fatigue, headaches
|
|
Oct. 23 2006
|
#3 Alimta/Avastin - Chemo Infusion
|
|
|
|
Nov 5 2006
|
|
Brain MRI - looks good
Chest CT - 3 nodules in question are half the size. Reduced in size from
7-8 mm to 2-3 mm. Everything else stable.
|
|
|
Nov 6 2006
|
|
Shoulder MRI - increased edema. No significant change in tumor.
|
Pain has decreased.
|
|
Nov 13 2006
|
#4 Alimta/Avastin - Chemo Infusion
|
|
Will continue on only Avastin until other decisions are made. Looking
for another targeted drug to add to it. Avastin is given IV every 3 wks.
|
|
Dec 5 2006
|
Avastin Only - Chemo Infusion
|
|
|
|
Dec. 13 2006
|
|
|
Saw Dr. Jack West, a lung cancer specialist at the Swedish Cancer Center
in Seattle. Very positive meeting. Sounds like there are many options
and that stopping all treatment for awhile might be worth considering.
|
|
Dec 2006
|
|
|
Developed osteonecrosis in jawbone from tooth extraction in September.
This is a spot on my gum that has exposed bone. This is a fairly common
occurrence among patients who have been on Zometa. It is also possible
that Avastin is to blame so I have stopped that drug to see if it will
heal on it's own.
|
|
2007
|
Treatment
|
Scans
|
Appointments / Notes
|
| Jan. 15 2007 |
|
CT Chest - spots appear larger in both lungs
CT Shoulder - no change
|
|
|
Jan. 19 2007
|
Back on Tarceva.
Continuing on 50 mg Vioxx.
|
|
|
|
Jan. 22 2007
|
Avastin - Chemo Infusion
|
|
|
|
aprox
|
Started Celebrex
|
|
Ran out of Vioxx,
|
|
Feb. 12 2007
|
Avastin - Chemo Infusion
Started on Lisinopril for high blood pressure (side effect of Avastin)
|
|
|
|
Feb. 28 2007
|
|
Chest CT - stable
Brain MRI - "looks lovely" :)
Jaw CT - small hole evident but not alarming right now.
|
|
|
Mar 5 2007
|
Avastin - Chemo Infusion
|
|
|
|
Mar 262007
|
Avastin - Chemo Infusion
|
|
|
|
April 11 2007
|
Switched back to 50 mg Vioxx
|
|
|
|
April 13 2007
|
|
Chest CT- progression of 3 nodules in right lung
Neck CT- clear
Shoulder CT- no change. MRI scheduled to confirm. Pain suggests
otherwise.
|
Significant shoulder and neck pain with decreased shoulder mobility for
past several wks.
|
|
April 16 2007
|
Avastin - Chemo Infusion
|
|
|
|
April 19, 2007
|
|
Shoulder MRI - new tumor seen on humeral head 6 mm. Additional swelling
and edema suggests other metastases that is not visible.
|
1000 mg Tylenol, Marcaine Injection, 15 mg Oxycodone for shoulder pain
during MRI
|
|
April 20, 2007
|
|
PET scan - Activity seen in tumor (13mm) in lower right lobe of lung
(SUV 5.7) and in three other tumors. Numerous other small areas in lung
appear active as well. Activity also seen throughout scapula, glenoid
and humoral head.
|
100 mg Tylenol, 10 mg Oxycodone, 5 mg Xanax for pain during scan.
|
|
April 23, 2007
|
Stopped Tarceva (aprox date)
|
|
B12 Injection in prep for Alimta
|
|
April 26, 2007
|
|
|
Met with Dr. Soronen, radiology oncologist. Decided to delay or cancel
rt. Small risk of nerve damage and other concerns. Hoping chemo will put
the brakes on it.
|
|
April 27, 2007
|
Alimta - Chemo Infusion
|
|
|
|
May 1, 2007
|
|
|
Talked to Dr. Udo Schmiedl at Seattle Radiology regarding radiation
options. After reviewing my film, he says RFA is not an option.
|
|
May 14, 2007
|
Begin radiation to shoulder, 15 treatments scheduled (1 daily)
|
|
Increased shoulder pain over past few wks
|
|
May 17, 2007
|
Alimta/Avastin - Chemo Infusion
|
|
|
|
June 4, 2007
|
Completed 15 radiation treatments
|
|
No significant improvement in shoulder yet
|
|
June 7, 2007
|
Alimta/Avastin - Chemo Infusion
|
|
Decrease in shoulder pain. Headaches.
|
|
June 13, 2007
|
|
Brain MRI - looked fine
Chest CT - numerous tumors in lungs show progression
|
G6PD Blood Test - negative (tests for an enzyme that would prevent the
admin of vit C)
|
|
June 19, 2007
|
|
|
Dr. Senecal - tentative plan is to try Sorafanib trial at Swedish with
Dr. West. If no response, try low weekly doses of Taxol (about 15%
chance of response) while waiting for vaccine trial to open in TX in 2-3
months.
|
|
June 21, 2007
|
Vitamin C 25 g IV
|
|
App with Dr. Gignac, ND, IV Vitamin C 25 g, started 300 mg lipoic acid.
|
|
June 22, 2007
|
|
|
app. with Dr. West at Swedish Cancer Center - provided details of two
trials. Surafanib and Sunitnib. Am considering them.
|
|
June 25, 2007
|
IV Vitamin C 50 g, B Complex, Mg
|
|
|
|
June 28, 2007
|
IV Vitamin C 50 g, B Complex, Mg
|
|
|
|
July 9
|
IV Vitamin C 50 g, B Complex, Mg
|
|
|
|
July 10
|
Began Sarafenib (Nexavar) Trial with Dr.
West
|
|
|
|
July 11
|
IV Vitamin C 50 g, B Complex, Mg
|
|
|
|
18th
|
IV Vitamin C 50 g, B Complex, Mg
|
|
Developed hand-foot syndrome (common effect of Surafenib)
|
|
July 20th
|
IV Vitamin C 50 g, B Complex, Mg
|
|
Shoulder continues to feel stable
|
|
July 23rd
|
IV Vitamin C 50 g, B Complex, Mg
|
Chest CT - no appreciable change
|
Increased coughing prompted scan. Since last scan was only 6 wks ago,
these results may not be reliable.
|
|
July 24th
|
IV Vitamin C 50 g, B Complex, Mg
|
|
Dr. Chu - discussed low dose chemo options
Dr. West - general eval
|
|
Aug 1st
|
IV Vitamin C 50 g, B Complex, Mg
|
|
|
|
Aug 3rd
|
IV Vitamin C 50 g, B Complex, Mg
|
|
|
|
Aug 7th
|
IV Vitamin C 50 g, B Complex, Mg
|
|
Dr. West - decided to stay on trial for 4 more weeks and then get scans
to assess response. Increased shortness of breath and coughing.
|
|
Aug 10th
|
IV Vitamin C 50 g, B Complex, Mg
|
|
|
|
Aug 14th
|
IV Vitamin C 50 g, B Complex, Mg
|
|
|
|
Aug 16th
|
IV Vitamin C 50 g, B Complex, Mg
|
|
|
|
Aug 20th
|
IV Vitamin C 50 g, B Complex, Mg
|
|
|
|
Aug 22nd
|
IV Vitamin C 70 g, B Complex, Mg
|
|
|
|
Aug 28th
|
|
Chest CT - of the 5 tumors they were following, 1 shrunk, 3 are stable,
1 grew.
|
|
|
Aug 30th
|
|
|
Dr. West - Discussed results. I will decide where to go from here.
|
|
Sept 11th
|
IV Vitamin C 70 g, B Complex, Mg
|
|
|
|
Sept 13th
|
IV Vitamin C 70 g, B Complex, Mg
|
|
|
|
Sept 21st
|
|
PET scan - everything is progressing. New lesion in sacrum, L4 vertebrae
and near pancreatic duct.
Brain MRI - OK
|
|
| Sept 26th |
|
|
Dr. Nemanaitis - Mary Crowley Medical Research Center, Dallas TX
Enrolled in vaccine trial to start in about 3 weeks. Will fly down there
for 16 monthly injections at a cost of $25,000 plus travel expenses!
|
|
Sept 28th - Oct. 12th
|
|
HOSPITAL
10/2/07 Chest CT - pancreatic mass seen, multiple masses in both lungs,
pleural effusion on both sides
10/7/07 Chest CT - increased pleural effusion, several tumors are
larger.
Brain CT - OK
|
Admitted to hospital for pancreatitis. Endoscopy to look for ulcer,
trouble breathing (multiple small pulmonary emboli suspected),
bronchoscopy, put on O2, chest CT, lung function tests, shoulder spasms,
Dr. Senecal started me on chemo drug Taxol. Thoracentesis to drain 1
liter of fluid from lung, rapid heart rate, cardiac ICU, echocardigram,
headaches, brain CT. Developed blood clot in vein near heart due to pic-line.
Vaccine trial on hold.
|
|
Oct. 8th
|
Taxol - low dose chemo infusion
|
|
Decision was made to begin chemo while in hospital to try and get
control of cancer in lungs. If cancer can be slowed or stopped, vaccine
may still be possibility.
|
| Oct. 16th |
Taxol - low dose chemo infusion
|
|
|
|
Oct. 22nd
|
Taxol - low dose chemo infusion
|
|
|
|
Oct. 29th
|
Taxol - low dose chemo infusion
|
|
Dr. Senecal
|
|
Nov. 2nd
|
|
EKG
|
Dr. Fahmy (radiologist) Follow up after episodes in hospital with rapid
heart rhythm and blood clot.
|
|
Nov 5th
|
Taxol - low dose chemo infusion
|
|
Dr. Senecal - is happy with how well I'm doing. Sounds somewhat
optimistic about attempting the vaccine in Dallas again if tumors have
shrunk.
|
|
Nov. 6th
|
|
Echocardiogram - Blood clot is now larger (about 1 x 2 cm) and has
dropped into right atrium. This formed when the pic-line was put in.
|
Dr. Fahmy (cardiologist) and Dr. Senecal discussed options. They have
decided to up the dose of Fragmin, the daily blood thinner injection
I've been giving myself to see if that will dissolve it.
|
|
Nov. 12th
|
Taxol - low dose chemo infusion
|
Chest CT - considerable improvement of the two largest tumors in lower
and middle right lung. From around 25mm each to about 8 mm each. Largest
tumor in left lung and primary tumor in right upper lung are unchanged
(both about 16mm) as is all other smaller nodules. No lymph node
involvement seen. No mediastinal masses seen. Prior moderate pleural
effusion now minimal.
|
|
| Nov. 19th |
Taxol - low dose chemo infusion
|
|
Dr. Senecal - 'pleasantly surprised' with scan results (details just
added above). He has a call in to Dr. Nemunaitis to discuss pursuing
vaccine trial again. Three more chemo doses planned.
|
|
Nov 20th
|
|
|
Dr. Fahmy - follow up to address thrombus in heart. Echocardiogram next
week see if it is shrinking.
|
|
Nov. 26th
|
Taxol - low dose chemo infusion
|
|
|
|
Nov. 27th
|
|
Echocardiogram - blood clot is about the same size.
|
|
|
Nov. 29th
|
|
|
Dr. Wang - acupunture and herbs to help boost immune system.
|
|
Dec. 3rd
|
Taxol - low dose chemo infusion
|
|
|
|
Dec. 4th
|
|
|
Call to Dallas. They informed me that the last vaccine was used on
another patient. Dr. there will see if he can get one more from maker.
Will continue on Taxol while we wait.
|
|
Dec. 10th
|
Taxol - low dose chemo infusion
|
Chest CT - a little better
Pelvic CT - Probable met on L4 as noted on earlier PET.
Brain MRI - OK
|
Saw Dr. Senecal and talked to nurse in Dallas. This was the last chemo.
Plan to go to Dallas in about one month for first of 16 vaccinations.
|
|
Dec. 19th
|
|
Doppler of Right Arm - no blood clots seen.
|
Pain/red streak running down vein in arm prompted a Doppler
(ultrasound).
|
|
2008
|
Treatment
|
Scans |
Appointment/Notes |
|
Jan. 14-18
|
Lucinix Vaccine #1 (1/17)
|
Chest/Pel/Ab CT - This was done in Dallas
for baseline. Not compared to prior scans. Volume loss in right middle
lobe. Multiple small nodules throughout both lungs as always. Bone mets
in vertebrae. Probably some progression since last scans.
Bone Scan - waiting for results |
In Dallas, TX Mary Crowley Medical
Research Center, Baylor Univ. for trial vaccine. Will continue monthly
trips for at least 10 months to get the vaccine. |
|
Feb. 6-7
|
Lucinix Vaccine #2 (2/7)
|
|
Dallas. Saw Dr. Olivares
|
|
Feb. 13
|
|
Brain MRI - 10- 20 small mets found.
|
Was having headaches so requested brain MRI.
|
|
Feb 14
|
|
|
Dr. Senecal - Went over brain scan results. Meet with GammaKnife doctor
tomorrow to see if there are any options. Whole brain radiation is not
possible a second time.
|
|
Feb 15
|
|
|
Saw Dr. Bergman, radiation oncologist in Tacoma. He wants to do
GammaKnife radiation to the most critical tumors.
Saw Dr. Mrugala and Dr. Rockhill at the U of W. They also want to do
GammaKnife. They also suggest a lumbar tap to look for cancer in spinal
fluid.
Number and size of brain mets varies depending on who you ask. There are
somewhere between 10-20 with the largest being somewhere between 4mm and
10mm. A high resolution MRI is scheduled to get more accurate
information.
|
|
Feb 20
|
Temador - chemo pill for brain mets (day
1 of 28 day cycle) |
|
Will take on days 1-5 on 28 day cycle.
|
|
Feb 21
|
|
|
Decided to get treatment in Tacoma. Gamma Knife Consultation with Dr.
Bergman. Discussed the procedure. Will take around 6 hrs from beginning
to end. Metal frame will be screwed into skull. Treatment will be done
on as many mets as possible.
|
|
Feb 25
|
GammaKnife Treatment, St. Joe's
Tacoma
|
Hi Res (3x contrast) Brain MRI - 10
confirmed tumors |
All 10 tumors were treated. Total
procedure lasted about 6 hrs. Dr. Bergman and Dr. Nells performed the
procedure |
|
Mar 3
|
|
Lung/Heart X-ray - to rule out cardiac/pulmonary cause of pain.
|
St. Joe's emergency. Went in with abdominal pain and was concerned it
may be pancreas related. Enzymes levels were normal though. They wanted
to do pelvic CT but I declined.
|
|
Mar 4-6
|
Lucinix Vaccine #3
|
Chest/Pelvic/Ab CT - unable to confirm but highly suggestive of
progression throughout chest. Moderately extensive patchy infiltrates
and multiple nodules increased in size.
|
Dallas - Saw. Dr. Nemunaitis. Because of the uncommon look of the
lungs, it cannot be confirmed whether there is progression or an immune
response occurring. 60% chance it's progression. He suggests waiting
another month and rescanning before pulling out of the study.
Considering that shortness of breath is significantly worse, I am quite
certain it is progression and am looking for other options.
|
|
Mar. 11
|
|
|
Dr. Chue - Seattle Cancer Wellness and Treatment Center. Discussed chemo
options such as low dose Gemzar/Taxol/Cytabine
|
|
Mar 12
|
|
|
Dr. Bergman - quick gamma knife follow up. Nothing significant
discussed.
|
|
Mar 13
|
|
|
Dr. Senecal - discussed scan results from Dallas. He wants to see me
next week again before we make treatment decision.
|
|
Mar 18
|
|
Echocardiogram - blood clot is smaller.
|
To evaluate status of blood clot.
|
|
Mar 20
|
Temodor - chemo pill for brain mets (day 1 of 28 day cycle)
|
Brain MRI - all tumors are smaller or stable.
|
Brain MRI at St. Joe's
Dr. Senecal - Wants to use Gemzar alone for chemo.
|
|
Mar 24
|
|
Bone Marrow MRI - bone mets on sacrum, L4, iliac wing, and right femur
(5mm)
|
TRA Gig Harbor |
|
Mar 27
|
Chemo infusion 1 - Gemzar 1500 mg
|
|
Weekly for 3 weeks then off 1 wk as long
as blood counts don't fall too low.
Dr. Bergman - follow up on GammaKnife. |
|
Ap 3
|
Chemo infusion 2 - Gemzar 1500 mg
|
|
Picked up O2 to have
at home. Having trouble with congestion in lungs. Started on
antibiotics (4/8) |
|
Ap 10
|
Chemo infusion 2 - Gemzar 1300 mg
|
|
Lower dose due to low white blood cells.
Started self injections of Nupoegen to stimulate WBC production. |
|
Ap 17 |
|
Chest CT - clear evidence of increased tumor growth.
|
Dr. Senecal - Symptoms are clearly worse.
Stopped Gemzar. Hoping to get into trial at U of W but there is a 30 day
washout requirement. He says I don't have 30 days. Trying to get
waiver from drug company to allow me to start right away. |
|
Ap 21 |
|
|
Dr. Martins, lung cancer specialist at U
of WA. We are planning on starting trial in 3 weeks. |
|
Ap 24 |
|
|
Dr. Senecal |
|
Ap 29 |
|
Chest/Ab/Pel CT -
Eye Exam - |
At Seattle Cancer Care Alliance (SCCA)
all day for scans, blood work, EKG, eye exam as required before entering
trial. |
|
Ap 30 |
|
Brain MRI - unable to complete |
At SCCA but was unable to complete due to
severe pressure in head. Sponsoring company agreed to waive the MRI. It
also sounds as though my original biopsy has enough tissue to test for
EGFR mutation so I will not need another biopsy. Started Prednisone
(steroid) to hopefully help breathing. |
|
May 1 |
|
|
Dr. Senecal quick checkup. |
|
May 8 |
|
|
Dr. Senecal quick checkup |
|
May 12 |
Begin trial IPI-504. Infusion 1 (Cycle 1) |
|
Seattle Cancer Care Alliance, Labs, Dr
Martins. |
|
May 13 |
Follow up Labs |
|
Seattle Cancer Care Alliance. Low
Potassium so started 60 mg |
|
May 15 |
Infusion IPI-504 Infusion 2 |
|
Seattle Cancer Care Alliance, |
|
May 19 |
IPI-504 -Opted Out Infusion 3 |
|
Breathing has continued to worsen.
Decided to not get treatment and think about whether to continue or not. |
|
May 23 |
IPI-504 Infusion 4 |
1 wk no drug on week of each cycle. |
Seattle Cancer Care Alliance. Decided to
get treatment. |
|
June 2 |
(Cycle 2) IPI-501 Infusion 1 |
|
Labs showed Glucose 198, high blood
pressure, high bp, |
|
June 2 |
|
Chest XR - blood clot is gone. Chest CT- Progression. |
Called 911, admitted to St. Joes due to racing heart, high
bp, shortness of breath and overall weakness.Cause of symptoms is still trying to be
determined. Discharged that
evening. |
|
June 18 |
Terri has stopped all treatment |
|
Terri is under Hospice care. |
|
July 4 |
Beautiful Terri died at home |
|
She was in her husbands arms |